Atopic Dermatitis in Skin of Colour Patients: A Clinically Practical Literature Review Summary
DOI:
https://doi.org/10.58931/cdt.2025.64153Abstract
The growing interest in understanding the nuances of dermatologic conditions across diverse ethnicities continues to gain momentum amongst practising dermatologists and residents. It is encouraging to see residency programs evolving to encompass a wider range of cases, both common and rare, from various ethnic backgrounds.
Atopic dermatitis is a common condition that every dermatologist encounters in their practice. However, its nuances in presentation amongst patients of varying skin tones can present significant challenges in diagnosis and management.
To gather the most up to date, clinically applicable knowledge in atopic dermatitis patients with skin of colour, a literature review of all systematic reviews published in the last 5 years on this topic was conducted. Three papers were chosen: Napolitano et al., Adawi et al., and Gan et al. The most clinically relevant aspects of these papers are summarized below.
References
Napolitano M, Fabbrocini G, Martora F, Genco L, Noto M, Patruno C. Children atopic dermatitis: diagnosis, mimics, overlaps, and therapeutic implication. Dermatol Ther. 2022;35(12):e15901. doi:10.1111/dth.15901
Adawi W, Cornman H, Kambala A, Henry S, Kwatra SG. Diagnosing atopic dermatitis in skin of color. Dermatol Clin. 2023;41(3):417-429. doi:10.1016/j.det.2023.02.003
Gan C, Mahil S, Pink A, Rodrigues M. Atopic dermatitis in skin of colour. Part 2: considerations in clinical presentation and treatment options. Clin Exp Dermatol. 2023;48(10):1091-1101. doi:10.1093/ced/llad162
Alexis A, Moiin A, Waibel J, Wallace P, Cohen D, Laquer V, Kwong P, Reck Atwater A, Schuster C, Proper J, Silk M, Pierce E, Pillai S, Rueda M, Moore A. Efficacy and Safety of Lebrikizumab in Adult and Adolescent Patients with Skin of Color and Moderate-to-Severe Atopic Dermatitis: Results from the Phase IIIb, Open-Label ADmirable Study. Am J of Clin Derm. 2025;26:803-817. Doi:10.1007/s40257-025-00970-8