Diluted and Hyperdiluted Calcium Hydroxyapatite For Skin Tightening

Authors

  • Malika Ladha, MD

Abstract

Biostimulatory fillers, such as calcium hydroxylapatite (CaHA), have been used for more than a decade for facial voluminization and HIV-induced lipoatrophy. Over the last few years, CaHA has also been increasingly utilized to tighten skin and improve skin quality. CaHA is a biodegradable and resorbable filler composed of microspheres suspended in an aqueous carboxymethyl cellulose gel carrier. The biostimulatory nature of CaHA distinguishes it from other fillers: while the carrier provides initial volume replacement, the particles induce a delayed fibroblast and histiocyte response leading to increased collagen and elastin formation, and ultimately dermal remodelling.

CaHA reconstitutions can be categorized based on ratios: none/undiluted, dilute (1:1), and hyperdiluted (≥1:2). In hyperdiluted forms, CaHA causes biostimulation without voluminization. Overall, this leads to skin tightening and improvement of various skin parameters, such as elasticity, firmness, superficial wrinkles, and overall appearance. The use of diluted and hyperdiluted CaHA for skin tightening is a relatively new technique growing in popularity. It can be used in various areas of the body such as the upper arms, abdomen, and thighs. Hyperdiluted CaHA has also been used to treat cellulite and striae. 

 

Author Biography

Malika Ladha, MD

Dr. Malika Ladha is a board-certified dermatologist in both the U.S. and Canada. She completed dermatology residency at the University of Calgary. During this time, she served as the Canadian Dermatology Association Resident and Fellow Society co-chairperson and initiated many national virtual learning initiatives. She was awarded the 2020 Resident Physician Mentorship and Teaching Award from the Professional Association of Residents of Alberta, the 2021 Resident Doctors of Canada Medical Education Award, and the 2021 Royal College of Physicians Resident Leadership Award. She is currently completing a clinical fellowship in Laser Surgery and Aesthetic Dermatology at the University of Toronto.

References

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Published

2022-03-01

How to Cite

1.
Ladha M. Diluted and Hyperdiluted Calcium Hydroxyapatite For Skin Tightening. Can Dermatol Today [Internet]. 2022 Mar. 1 [cited 2024 Nov. 9];3(1):16–19. Available from: https://canadiandermatologytoday.com/article/view/3-1-ladha

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Articles