Avancées dans le domaine du vitiligo : Physiopathologie, conséquence psychosociale et thérapie émergente
Résumé
Le vitiligo est une maladie chronique auto-immune de la peau qui touche environ 0,5 à 2 % de la population mondiale. Il se caractérise par la perte des mélanocytes producteurs de pigments, ce qui se traduit par des taches dépigmentées sur la peau. Il touche indifféremment tous les sexes et toutes les couleurs de peau. Bien qu’il puisse apparaître à tout âge, 50 % des personnes touchées voient leur maladie se manifester avant l’âge de 20 ans. Les progrès récents de la recherche sur le vitiligo ont permis de mieux comprendre sa physiopathologie, son épidémiologie et son impact psychosocial sur les patients. Alors que les options thérapeutiques traditionnelles n’ont eu qu’un effet limité, plusieurs thérapies émergentes sont en cours de développement et pourraient bientôt être disponibles pour les patients canadiens atteints de vitiligo.
Références
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Feng Y, Lu Y. Advances in vitiligo: update on therapeutic targets. Front Immunol. 2022;13:986918. doi:10.3389/ fimmu.2022.986918
