Recommendations and Basic Principles of Phototherapy
DOI:
https://doi.org/10.58931/cdt.2025.61134Abstract
Phototherapy has long been a cornerstone in dermatology, offered in most dermatology clinics globally. Despite the advent of several new biologic and systemic therapeutics, phototherapy remains a favoured treatment option due to its low side-effect profile and efficacy for treating mild-to-moderate inflammatory dermatoses. It can be used for a variety of skin conditions, including psoriasis, eczema, vitiligo, lichen planus, mycosis fungoides, pityriasis lichenoides, nodular prurigo, pruritus, and morphea.
In this article, we will provide an overview of the basic principles of phototherapy, as well as offering recommendations for managing a phototherapy service. Our focus will be on whole-body phototherapy, without the use of psoralens.
References
Ferguson J, Dover J. Photodermatology. 1st ed. London: CRC Press; 2006. doi: 10.1201/b15138
Lim HW, Honigsmann H, Hawk JLM, editors. Photodermatology. 1st ed. London: CRC Press; 2019
Bolognia JL, Schaffer JV, Cerroni L. Dermatology. 4th ed. Philadelphia: Elsevier; 2017.
Kang S, Amagai M, Bruckner AL, Enk AH, Margolis DJ, McMichael AJ, et al. Fitzpatrick’s dermatology, 9th ed. New York: McGraw-Hill Education; 2019.
Goulden V, Ling TC, Babakinejad P, Dawe R, Eadie E, Fassihi H, et al. British Association of Dermatologists and British Photodermatology Group guidelines for narrowband ultraviolet B phototherapy 2022. Br J Dermatol. 2022;187(3):295-308. doi:10.1111/bjd.21669
Elmets CA, Lim HW, Stoff B, Connor C, Cordoro KM, Lebwohl M, et al. Joint American Academy of Dermatology–National Psoriasis Foundation guidelines of care for the management and treatment of psoriasis with phototherapy. J Am Acad Dermatol. 2019;81(3):775-804. doi: 10.1016/j.jaad.2019.04.042
Fitzpatrick TB. The validity and practicality of sunreactive skin types I through VI. Arch Dermatol. 1988;124(6):869-871. doi:10.1001/archderm.124.6.869
Alrashidi A, Rhodes LE, Sharif JC, Kreeshan FC, Farrar MD, Ahad T. Systemic drug photosensitivity—Culprits, impact and investigation in 122 patients. Photoderm Photoimmunol Photomed. 2020;36(6):441-451. doi:10.1111/phpp.12583
Ahad T, Rhodes LE. Haemorrhagic vesicles and varioliform scarring: consider photosensitivity. Arch Dis Child. 2020;105(3):302-303. doi: 10.1136/archdischild-2018-316272
Ahad T, Wang EY, Liu YA, Lee TK, Lui H, Crawford RI, et al. Incidence of skin cancers in patients with eczema treated with ultraviolet phototherapy. Journal of the Am Acad Dermatol. 2022;87(2):387-389. doi: 10.1016/j.jaad.2021.11.048
Wang E, Ahad T, Liu YA, Lee TK, Lui H, Crawford RI, et al. Incidence and profile of skin cancers in patients following ultraviolet phototherapy without psoralens: a retrospective cohort study. J Am Acad Dermatol. 2024;90(4):759-766.
